Dose Response Oxidation of a Sweet-corn Derived Sugar (PhytoSpherix) During Exercise in Endurance Trained Athletes

Summary

PhytoSpherix (Phx) is an all-natural, edible polysaccharide extracted from sweet corn. This carbohydrate is the major muscle fuel for intense exercise and its stores are quite small such that one can run out of it during a single exercise bout. Therefore, Phx should provide significant exercise fuel if consumed during exercise. As a result its intake could enhance intense exercise performance by providing additional fuel. This experiment Will investigate the effects of 4 different dosages of Phx consumed throughout a prolonged exercise bout on carbohydrate and fat utilization as well as its oxidation rate and perception of effort during prolonged intense exercise in trained cyclists. Muscle and liver carbohydrate stores will be examined using a non-invasive ultrasound technique.

Conditions

• Hypoglycemia

Interventions

DIETARY_SUPPLEMENT

Use of PhytoSpherix at 0 g/min

PhytoSpherix (Sweet-corn derived sugar) will be fed at 0 g/min during a 150 min cycling exercise

DIETARY_SUPPLEMENT

Use of PhytoSpherix at 1 g/min

PhytoSpherix (Sweet-corn derived sugar) will be fed at 1 g/min during a 150 min cycling exercise

DIETARY_SUPPLEMENT

Use of PhytoSpherix at 1.5 g/min

PhytoSpherix (Sweet-corn derived sugar) will be fed at 1.5 g/min during a 150 min cycling exercise

DIETARY_SUPPLEMENT

Use of PhytoSpherix at 2 g/min

PhytoSpherix (Sweet-corn derived sugar) will be fed at 2 g/min during a 150 min cycling exercise

BEHAVIORAL

Cycling exercise

Male endurance athletes will complete a cycling exercise for 150 min at 50% of their respective maximum wattage

Sponsors & Collaborators

• Mirexus Biotechnologies Inc

  collaborator UNKNOWN

• University of Western Ontario, Canada

  lead OTHER

Principal Investigators

• Peter Lemon, PhD · Western University

Study Design

Allocation

NA

Purpose

BASIC_SCIENCE

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

30 Years

Sex

MALE

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2016-09-30

Primary Completion

2017-09-30

Completion

2017-09-30

Countries

• Canada

Study Locations