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Intestinal Sweet Taste Receptor Function and Adaptation to Dietary Sugars and Sweeteners

NCT02835859 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2020-08-14

No results posted yet for this study

Summary

The purpose of this study is to collect data that will help researchers better understand the various causes of obesity and diabetes; particularly to understand how consumption of NCASs affects the way the body uses nutrients.

Conditions

Interventions

OTHER

Dietary: saccharin

Assess the glycemic and hormonal responses to an oral glucose load preceded by an oral solution of NCASs (saccharin).

OTHER

Estimate glucose absorptions

Indirectly estimate the rate of glucose absorption and gastric emptying by using 3-O-methyglucose (3-OMG) and acetaminophen, respectively.

Sponsors & Collaborators

  • Sanford-Burnham Medical Research Institute

    collaborator OTHER

  • AdventHealth Translational Research Institute

    lead OTHER

Principal Investigators

  • George Kyriazis, PhD · Study Principal Investigator

Study Design

Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-08-31
Primary Completion
2016-01-31
Completion
2017-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02835859 on ClinicalTrials.gov