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Botanical Oils Study to Determine Genetic Differences in the Way Your Body Processes Fats in Edible Oils

NCT02337231 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 66

Last updated 2018-08-14

No results posted yet for this study

Summary

A randomized, controlled, cross-over clinical trial of borage oil vs soybean oil to determine whether the metabolism and/or impact of medium chain-polyunsaturated fatty acids (MC-PUFAs) in botanical oil supplements are changed in relationship to specific genotypes in a SNP (rs174537) strongly associated with FADS1 activity and PUFA metabolism.

Conditions

  • Genetic Differences of Lipid Metabolism/Healthy Subjects

Interventions

DIETARY_SUPPLEMENT

soybean oil and borage oil

Compare the capacity of humans with GG, GT and TT genotypes at rs174537 taking soybean and borage oils to metabolize medium chain PUFAs.

Sponsors & Collaborators

  • National Center for Complementary and Integrative Health (NCCIH)

    collaborator NIH

  • Office of Dietary Supplements (ODS)

    collaborator NIH

  • Wake Forest University Health Sciences

    lead OTHER

Principal Investigators

  • Floyd H. Chilton, Ph.D. · Wake Forest Health Science

  • Priscilla Ivester, M.S. · Wake Forest Health Science

  • Tammy Lee, M.S. · Wake Forest Health Science

  • Susan Sergeant, Ph.D. · Wake Forest Health Science

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-06-24
Primary Completion
2015-12-15
Completion
2015-12-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02337231 on ClinicalTrials.gov