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Modulation of Insulin Sensitivity by Betaine Upregulation of FGF21

NCT02118142 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 23

Last updated 2014-08-12

No results posted yet for this study

Summary

People with poor insulin sensitivity do not respond normally to elevations in blood sugar. This may increase their risk of developing diabetes in the future. The purpose of this research study is to determine if the nutrient betaine, found in beets, spinach and wheat products, can enhance the production of fetal growth factor 21 (FGF21), a molecule that is believed to promote insulin sensitivity.

Conditions

  • Insulin Sensitivity

Interventions

DIETARY_SUPPLEMENT

Betaine

6 gram one-time dose of betaine delivered in encapsulated form with an unsweetened beverage

DIETARY_SUPPLEMENT

Dextrose

6 gram one-time dose of dextrose delivered in encapsulated form with an unsweetened beverage

Sponsors & Collaborators

  • UNC Nutrition Research Institute

    lead OTHER

Principal Investigators

  • Karen Corbin, PhD, RD · UNC Nutrition Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
TRIPLE
Model
CROSSOVER

Eligibility

Min Age
21 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-03-31
Primary Completion
2014-07-31
Completion
2014-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02118142 on ClinicalTrials.gov