Differential Effects of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Platelet, Endothelial and Vascular Function
NCT01735357 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 48
Last updated 2019-09-16
Summary
The purpose of this study was to determine whether supplementation with oils enriched with long chain n-3 PUFA, either EPA or DHA, had a differential effect on platelet, endothelial and vascular function.
Conditions
- Healthy
Interventions
- DIETARY_SUPPLEMENT
-
EPA-rich triacylglycerol oil
- DIETARY_SUPPLEMENT
-
Placebo - olive oil (BP specification)
- DIETARY_SUPPLEMENT
-
DHA-rich triacylglycerol oil
Sponsors & Collaborators
- lead OTHER
Principal Investigators
-
Wendy L Hall, PhD · King's College London
Study Design
- Allocation
- RANDOMIZED
- Purpose
- PREVENTION
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 45 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-06-30
- Primary Completion
- 2010-04-30
- Completion
- 2010-04-30
Countries
- United Kingdom
Study Locations
More Related Trials
-
A Dose Response Investigation of Docosahexaenoic Acid (DHA)
NCT06294067 ·Status: COMPLETED ·Phase: PHASE1
-
The Effects of Omega-3 Fatty Acids Supplementation on Endothelial Function and Inflammation
NCT01310270 ·Status: COMPLETED ·Phase: NA
-
A Study of Different Types of Fatty Acid on Risk Factors for Heart Disease
NCT01351324 ·Status: COMPLETED ·Phase: NA
-
Eicosapentaenoic Acid (EPA)and Docosahexaenoic Acid Study
NCT01400490 ·Status: UNKNOWN ·Phase: NA
-
The Effects of Omega-3 Fatty Acids on Peripheral Arterial Disease II
NCT01979874 ·Status: COMPLETED ·Phase: PHASE2
-
Role of Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) on Inflammation and Lipids
NCT02670382 ·Status: COMPLETED ·Phase: NA
-
Comparison of EPA and DHA-Rich Fish Oils on Lipoprotein Metabolism In Adults
NCT02514070 ·Status: COMPLETED ·Phase: PHASE2
-
Fish Oil-derived N-3 Polyunsaturated Fatty Acids and Extracellular Vesicles
NCT03203512 ·Status: COMPLETED ·Phase: NA
-
Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in Adults
NCT03372733 ·Status: RECRUITING ·Phase: PHASE2
-
Effects of Omega-3 Fatty Acids in Ambient Air Pollution Exposure in Healthy Adults
NCT02921048 ·Status: COMPLETED
-
The Use of Fish Oil to Reduce Inflammation Caused by a Peripheral Vascular Intervention
NCT02096757 ·Status: COMPLETED ·Phase: NA
-
Docosahexenoic Acid (DHA) Supplementation and Cardiovascular Disease in Men With High Triglycerides
NCT00728338 ·Status: COMPLETED ·Phase: NA
-
Fish Oil and Cardiovascular Suboptimal Health
NCT02103517 ·Status: COMPLETED ·Phase: PHASE3
-
Impact of EPA and DHA Supplementation on Plasma Biomarkers of Inflammation (n3)
NCT01810003 ·Status: COMPLETED ·Phase: NA
-
Omega-3 Fatty Acids Supplementation and Atherothrombotic Biomarkers in Type 2 Diabetes and Cardiovascular Disease.
NCT02178501 ·Status: COMPLETED ·Phase: NA
-
Effects of N-3 Polyunsaturated Fatty Acids On Chylomicron Secretion And Expression Of Genes That Regulate Intestinal Lipid Metabolism In Men With Type 2 Diabetes
NCT01449773 ·Status: COMPLETED ·Phase: NA
-
Systematic Review and Meta-analysis of the Differential Effects of DHA and EPA on Inflammation
NCT03520556 ·Status: COMPLETED
-
Impacts of Omega-3-PUFA Enriched Chicken-meat and Eggs in Healthy Humans
NCT04127409 ·Status: COMPLETED ·Phase: NA
-
Polyunsaturated Fatty Acids Supplementation and Blood Metabolome
NCT03892486 ·Status: UNKNOWN ·Phase: NA
-
Omega-3 to Reduce Diabetes Risk in Subjects With High Number of Particles That Carry "Bad Cholesterol" in the Blood
NCT04496154 ·Status: COMPLETED ·Phase: NA
-
Effect of 12 wk of Omega-3 FA Supplementation on Metabolic and Physical Health Parameters in Older Adults
NCT01734538 ·Status: UNKNOWN ·Phase: NA
-
Fatty Acid Metabolism in Carriers of Apolipoprotein E Epsilon 4 Allele: Determining the Blood-to-brain Link
NCT04279743 ·Status: UNKNOWN ·Phase: NA
-
A Study in Healthy Subjects to Compare the Bioavailability of EPA + DHA
NCT06629103 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE4
-
The Effects of Fish Oil Supplementation on the Brain Health of Collegiate Football Athletes
NCT04796207 ·Status: COMPLETED ·Phase: NA
-
Effects of Omega-3 Fatty Acids on Markers of Inflammation
NCT01129050 ·Status: COMPLETED ·Phase: NA