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Effects of Tocotrienols Supplementation on Platelet Aggregation in Subjects With Metabolic Syndrome

NCT01631838 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 32

Last updated 2013-12-20

No results posted yet for this study

Summary

The objective of this study is to address the anti-thrombotic effects of tocotrienols supplementation via modulation of platelet activation, thrombotic markers, inflammatory markers and endothelial function.

It is hypothesized that 2 weeks supplementation of tocotrienols will be able to suppress platelet aggregation in subjects with metabolic syndrome.

Conditions

  • Metabolic Syndrome
  • Platelet Aggregation, Spontaneous

Interventions

DIETARY_SUPPLEMENT

Tocotrienol-rich fraction 400mg

Tocovid Suprabio 200mg is taken twice daily (after breakfast and dinner) for 2 weeks. During postprandial day (Day 14), subjects are requested to consume breakfast meal containing 50g of fat and 100mL of milkshake, follow by capsule consumption

DIETARY_SUPPLEMENT

Placebo

Placebo is taken twice daily (after breakfast and dinner) for 2 weeks. During postprandial day (Day 14), subjects are requested to consume breakfast meal containing 50g of fat and 100mL of milkshake, follow by capsule consumption

Sponsors & Collaborators

  • Universiti Putra Malaysia

    collaborator OTHER

  • Malaysia Palm Oil Board

    lead OTHER_GOV

Principal Investigators

  • Ju Yen Fu, PhD · Malaysia Palm Oil Board

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
25 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-05-31
Primary Completion
2012-08-31
Completion
2013-10-31

Countries

  • Malaysia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01631838 on ClinicalTrials.gov