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NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event

NCT01578629 · Status: COMPLETED · Phase: PHASE1/PHASE2 · Type: INTERVENTIONAL · Enrollment: 210

Last updated 2021-09-20

No results posted yet for this study

Summary

A natural form of vitamin E called tocotrienol (TCT), found in many common foods such as barley, decreases stroke size in animal models. Vitamin E has blood-thinning properties and lowers cholesterol, which make it a potential therapy for stroke prevention, though these effects are less well characterized for TCT. We plan to conduct two trials (I \& IIA) to determine the effects of orally supplemented TCT on platelet function and cholesterol.

Conditions

Interventions

OTHER

Vitamin E tocotrienol (TCT) capsules ; Low dose Aspirin

Vitamin E TCT capsules- 400-800 mg Aspirin- 81 mg

OTHER

Placebo vehicle control

vehicle control compared to Vitamin E TCT pills

Sponsors & Collaborators

  • Government of Malaysia

    collaborator UNKNOWN

  • Andrew Slivka

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-03-31
Primary Completion
2018-11-30
Completion
2018-12-31

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01578629 on ClinicalTrials.gov