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Exploring Learning and Unlearning of Fear

NCT01512316 · Status: WITHDRAWN · Phase: NA · Type: INTERVENTIONAL

Last updated 2023-01-31

No results posted yet for this study

Summary

The present study investigates the effect of d-cycloserine on learning and unlearning of fear in healthy humans and its underlying effect on the amygdala.

As a second objective, the effect of genotype on fear learning will be studied.

Conditions

  • Healthy Individuals

Interventions

DRUG

d-Cycloserine

250mg, one dose, 2hrs prior to fMRI

DRUG

Lactose pill

one dose, 2hrs prior to fmri

GENETIC

Saliva sample

Buccal cell material will be sampled from all participants on day3

OTHER

Functional neuroimaging (fMRI)

Sponsors & Collaborators

  • Universitaire Ziekenhuizen KU Leuven

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Countries

  • Belgium

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01512316 on ClinicalTrials.gov