Effectiveness of D-Cycloserine as an Aid to Enhance Learning for Individuals With OCD Receiving Behavior Therapy
NCT00182000 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 33
Last updated 2012-07-16
Summary
This study will assess the effectiveness of Seromycin (D-cycloserine) in enhancing the positive effects of behavior therapy for people with Obsessive-Compulsive Disorder (OCD).
Conditions
- Obsessive-Compulsive Disorder
Interventions
- DRUG
-
seromycin
100mg tablet administered 1 hour prior to each therapy session
- BEHAVIORAL
-
Behavior Therapy
10 weekly hour-long behavior therapy sessions
Sponsors & Collaborators
-
Hartford Hospital
collaborator OTHER -
Massachusetts General Hospital
lead OTHER
Principal Investigators
-
Sabine Wilhelm, Ph.D. · Massachusetts General Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- QUADRUPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2003-11-30
- Primary Completion
- 2008-01-31
More Related Trials
-
Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder
NCT02066792 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
D-Cycloserine as an Adjunct to Internet-CBT for OCD
NCT01649895 ·Status: COMPLETED ·Phase: PHASE4
-
A Placebo-Controlled Trial of D-Cycloserine and Exposure Therapy for Combat-PTSD
NCT00371176 ·Status: COMPLETED ·Phase: NA
-
2/2 D-Cycloserine Augmentation of CBT for Pediatric OCD
NCT01404208 ·Status: COMPLETED ·Phase: NA
-
Translational Approach to the Understanding and Treatment of Obsessive-Compulsive Disorder (OCD). Can D-Cycloserine Enhance and Stabilize the Treatment-response in Relapsed and Non-responding OCD-patients?
NCT02656342 ·Status: COMPLETED ·Phase: PHASE4
-
D-Cycloserine Augmentation of Behavior Therapy for Individuals With Body Dysmorphic Disorder
NCT00842309 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Augmenting Exposure Therapy With an N-Methyl-D-Aspartate (NMDA) Agonist for Panic Disorder
NCT00131339 ·Status: COMPLETED ·Phase: NA
-
D-Cycloserine Augmentation of Exposure and Response Prevention Treatment for Obsessive-Compulsive Disorder
NCT00257361 ·Status: WITHDRAWN ·Phase: PHASE2
-
Cognitive Behavioral Therapy Plus Drug Treatment for Obsessive Compulsive Disorder
NCT00045903 ·Status: COMPLETED ·Phase: NA
-
Effect of D-cycloserine on Extinction of Fear Conditioning
NCT00352586 ·Status: COMPLETED
-
Augmentation of Psychotherapy With D-Cycloserine in Agoraphobia
NCT01928823 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of D-cycloserine Plus Cognitive Behavioral Therapy on People With Social Phobia
NCT00515879 ·Status: COMPLETED ·Phase: PHASE3
-
Examining the Usage of Dopamine Blockers in OCD Patients
NCT00496925 ·Status: COMPLETED
-
D-cycloserine Augmented CBT for Panic Disorder
NCT01680107 ·Status: TERMINATED ·Phase: PHASE3
-
Developing Effective Response Inhibition Training for Symptom Relief in OCD and Trichotillomania
NCT02059980 ·Status: COMPLETED ·Phase: NA
-
Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
NCT05232032 ·Status: RECRUITING ·Phase: PHASE2
-
The Use of D-Cycloserine to Augment CBT for Pediatric OCD
NCT01687140 ·Status: UNKNOWN ·Phase: PHASE2
-
Pilot Study of Minocycline (NPL-2003) in Adults With Obsessive-Compulsive Disorder (OCD)
NCT00728923 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study.
NCT03356483 ·Status: COMPLETED ·Phase: PHASE1
-
Use of an Antibiotic as an Enhancer for the Treatment of Social Phobia
NCT00128401 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy of Agomelatine in Patients With Obsessive-Compulsive Disorder
NCT01108393 ·Status: COMPLETED ·Phase: PHASE2
-
D-Cycloserine Enhancement of Exposure in Social Phobia
NCT00633984 ·Status: COMPLETED ·Phase: PHASE4
-
Cannabinoid Medication for Adults With OCD
NCT02911324 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Neurofeedback for Obsessive-Compulsive Disorder (OCD)
NCT02206945 ·Status: COMPLETED ·Phase: NA
-
Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD
NCT01695291 ·Status: COMPLETED ·Phase: PHASE2