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Neurobiology of Generalized Fear-Conditioning & Avoidance in Anxiety Disorders

NCT03033056 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 208

Last updated 2022-03-10

No results posted yet for this study

Summary

Anxiety disorders are among the most prevalent, costly, and disabling mental illnesses. One central, yet largely understudied, abnormality in anxiety disorders is the heightened tendency to display fear and avoidance in reaction to benign or safe events that resemble feared situations. The current project maps brain circuits associated with this abnormality in order to contribute to future brain-based diagnosis and treatments for clinical anxiety.

Conditions

  • Anxiety Disorders

Interventions

BEHAVIORAL

Test of fear conditioning

Behavioral and brain correlates of conditioned fear generalization and avoidance will be assessed using fMRI and related to levels of anxiety related psychopathology.

Sponsors & Collaborators

Principal Investigators

  • Shmuel Lissek, PhD · U of MN

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-07-17
Primary Completion
2021-08-01
Completion
2021-08-01

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03033056 on ClinicalTrials.gov