Polscope Sperm: A Non-invasive Method to Assess DNA Damage in Individual Sperm
NCT01461395 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 84
Last updated 2012-08-24
Summary
The purpose of this study is to find a non-invasive way to discover DNA (deoxyribonucleic acid, which is the genetic material inside your cells) alterations in the sperm's head, in the near future leading us to choose the "good sperm" in a simplified manner. This could then increase chances of a successful in-vitro fertilization (IVF) treatment when there are sperm abnormalities.
Conditions
- DNA Damage
- Other Complications Associated With Artificial Fertilization
Sponsors & Collaborators
-
University of South Florida
lead OTHER
Principal Investigators
-
Celso Silva, M.D · University of South Florida
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2008-10-31
- Primary Completion
- 2012-06-30
- Completion
- 2012-06-30
Countries
- United States
Study Locations
More Related Trials
-
Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility Treatment
NCT05846256 ·Status: UNKNOWN
-
sperDNA Fragmentation a a Predictor for Outcome After Varicocelectomy,m
NCT07144891 ·Status: NOT_YET_RECRUITING
-
Reproductive Outcomes of Different Sperm Selection Techniques for ICSI Patients With Abnormal Sperm DNA Fragmentation.
NCT04482517 ·Status: COMPLETED ·Phase: NA
-
DNA Damage and Subfertility in Males - Impact on ART Outcome
NCT04160208 ·Status: UNKNOWN
-
DNA Damage and Subfertility in Males - Lifestyle Interventions to Improve Male Fertility and Health
NCT04183374 ·Status: UNKNOWN ·Phase: NA
-
Study of the ZyMōt Sperm Selection Method and Its Effect on Embryo Ploidy.
NCT06384794 ·Status: RECRUITING ·Phase: NA
-
Level of DNA-fragmentation Before and After Antioxidant-based Therapies in Male Infertility
NCT06050031 ·Status: NOT_YET_RECRUITING
-
Relationship Between Sperm Head Vacuoles and Sperm DNA Alterations in Infertile Men
NCT02006446 ·Status: COMPLETED
-
Impact of DNA Fragmentation in Sperm on Pregnancy Outcome After Intra-uterine Insemination in a Spontaneous Cycle
NCT03319654 ·Status: COMPLETED ·Phase: NA
-
Royal Jelly Supplementation in Unexplained Male Infertility
NCT07337265 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
The Paternal Clock: Uncovering the Consequences of Advanced Paternal Age on Sperm DNA Fragmentation
NCT05894356 ·Status: COMPLETED
-
Genetic Abnormalities and Oxidative Stress in Sperm as Cause of Recurrent Miscarriage.
NCT00447395 ·Status: COMPLETED
-
Relationship Between Nitric Oxide (NO) in Follicular Fluid and Sperm Fertilization Ability
NCT03307655 ·Status: UNKNOWN ·Phase: NA
-
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
NCT05903859 ·Status: RECRUITING ·Phase: PHASE3
-
Reliability for the Detection of Sperm DNA Damage by a Sperm Chromatin Dispersion Test (Halosperm)
NCT02252510 ·Status: COMPLETED
-
Effect of Sorting of Apoptotic Spermatozoa on the Outcome of Assisted Reproduction
NCT02166567 ·Status: COMPLETED ·Phase: NA
-
Evaluation of New Semen Collection & Transportation Kit
NCT04536545 ·Status: COMPLETED
-
The Efficiency of a New Sperm-Wash Device for Intrauterine Insemination in Couples With Infertility
NCT06956287 ·Status: RECRUITING ·Phase: NA
-
Sperm Selection by Either PICSI or MACS in Cases With Abnormal Sperm DNA Fragmentation Index for ICSI
NCT03398317 ·Status: COMPLETED ·Phase: NA
-
Oxidative Stress In Semen And Male Infertility
NCT03464656 ·Status: UNKNOWN ·Phase: PHASE4
-
Evaluation Study Between Density Gradient and Swimming Down for Semen Processing
NCT02329704 ·Status: COMPLETED
-
Impact of Telomere Biology and Sperm DNA Fragmentation on Embryonic Development
NCT05508217 ·Status: RECRUITING
-
Aneuploidies in Embryos and Spermatozoa From Patients With Y-chromosome Microdeletions
NCT02527954 ·Status: TERMINATED
-
Modern Analyses of the Semen in Evaluating Male Fertility and Treatment Options of Male Infertility
NCT02932865 ·Status: COMPLETED
-
Can the Origin of Sperm Affect Embryo Ploidy in Patients With Severe Male Factor Infertility?
NCT06476379 ·Status: COMPLETED ·Phase: NA