MedTrace Logo

Reproductive Outcomes of Different Sperm Selection Techniques for ICSI Patients With Abnormal Sperm DNA Fragmentation.

NCT04482517 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 320

Last updated 2020-07-22

No results posted yet for this study

Summary

Comparing the reproductive outcomes of different sperm selection techniques; Density gradient centrifugation (DGC), Testicular sperm (Testi), Physiological ICSI (PICSI), and Magnetic activated cell sorting (MACS) in abnormal sperm DNA fragmentation (SDF) ICSI patients.

Conditions

  • Infertility, Male

Interventions

OTHER

Density Gradient Centrifugation

Semen processing is done by double layer density gradient method.

OTHER

Physiological ICSI

Sperm selection by PICSI dishes depending on hyaluronan binding of sperm head

OTHER

Magnetic activated cell sorting

Sperm selection by using Annexin V micro-beads and separation columns

OTHER

Testicular sperm

Using testicular sperm retrieved by TESA or TESE

Sponsors & Collaborators

  • Ganin Fertility Center

    lead OTHER

Principal Investigators

  • Eman Hasanen · Ganin Fertility Center

  • khaled Elqusi · Ganin Fertility Center

  • Salma Eltanbouly · Ganin Fertility Center

  • Samar Gamal · Ganin Fertility Center

  • Abd ElGhafar Hussin · Ganin Fertility Center

  • Hanaa Elkhadr · Ganin Fertility Center

  • Hosam Zaki · Ganin Fertility Center

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-01
Primary Completion
2018-12-01
Completion
2018-12-01

Countries

  • Egypt

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04482517 on ClinicalTrials.gov