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Level of DNA-fragmentation Before and After Antioxidant-based Therapies in Male Infertility

NCT06050031 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 78

Last updated 2024-05-08

No results posted yet for this study

Summary

The investigators will investigate the effect of antioxidants and lifestyle factors on the level of oxidative stress. As oxidative stress cannot be directly measured, it will be approximated by the DNA fragmentation index (DFI) which reflects the level of DNA damage in sperm caused by oxidative stress.

Conditions

  • Infertility, Male

Interventions

DIETARY_SUPPLEMENT

Intake of antioxidant supplement

All participants will supplent oral antioxidants (individual or combined which can be obtained without prescription, and which are not regulated as a pharmaceutical drug) over three months.

Sponsors & Collaborators

  • Janna Pape

    lead OTHER

Principal Investigators

  • Michael von Wolff, Prof · Universitätsklinik fur Frauenheilkunde, Inselspital Bern

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-31
Primary Completion
2025-06-30
Completion
2025-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06050031 on ClinicalTrials.gov