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Performance Evaluation of Four Pharmacokinetic-Pharmacodynamic(PKPD) Models of Propofol in Elderly Patients

NCT01435785 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14

Last updated 2017-03-29

No results posted yet for this study

Summary

Despite the wide use of propofol target-controlled infusion (TCI) in elderly patients, pharmacokinetic (PK) and pharmacodynamic (PD) models performance has not been prospectively assessed in this population. The aims of this study are to derive four PKPD models using previously published PK parameters sets, and to prospectively assess their performance in elderly people. With the obtained data we propose to build a specific PKPD model for this population.

Conditions

  • Propofol Overdose of Undetermined Intent

Sponsors & Collaborators

  • Pontificia Universidad Catolica de Chile

    collaborator OTHER

  • Universidad del Desarrollo

    lead OTHER

Principal Investigators

  • Pablo O Sepulveda, MD · Clinica Alemana Universidad del Desarrollo

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2011-04-30
Primary Completion
2011-09-30
Completion
2011-12-31

Countries

  • Chile

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01435785 on ClinicalTrials.gov