the Effect Site Equilibration Time of Propofol is Age Dependant
NCT01586013 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 45
Last updated 2012-04-26
Summary
This study obtains an effect site model for White (Modified Marsh) pharmacokinetic propofol model. The plasma effect-site rate constant (ke0) obtained is affected by age.
Conditions
- Healthy
Interventions
- DRUG
-
evaluation of propofol effect using BIS
propofol administered in target controlled infusion using the pharmacokinetic model of White
Sponsors & Collaborators
-
Universidad del Desarrollo
lead OTHER
Principal Investigators
-
Pablo O Sepulveda, Dr · Clinica Alemana Universidad del Desarrollo
Study Design
- Allocation
- NA
- Purpose
- HEALTH_SERVICES_RESEARCH
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2010-10-31
- Primary Completion
- 2011-08-31
- Completion
- 2011-08-31
Countries
- Chile
Study Locations
More Related Trials
-
Reevaluation Prediction of the Effect Site Propofol Eleveld Model Using Slow and Fast Induction
NCT07237477 ·Status: COMPLETED
-
Slow Stepwise Propofol TCI Induction for Titration Anesthesia Maintenance
NCT02999126 ·Status: UNKNOWN ·Phase: PHASE4
-
Determination of Propofol Target Concentration for Young and Elderly by Suppression Rate Analysis
NCT03283410 ·Status: WITHDRAWN ·Phase: PHASE4
-
Relationship Between Bispectral Index, EEG Features, and Propofol Effect-site Concentration in Young and Elderly Patients.
NCT04774120 ·Status: COMPLETED
-
Influence of Equilibration Rate Constant (ke0) of Propofol on the Effect Site Concentration for Loss of Consciousness
NCT01091350 ·Status: COMPLETED ·Phase: NA
-
Remifentanil Effect on Burst Suppression Ratio
NCT06237101 ·Status: RECRUITING ·Phase: NA
-
Validation of a Pharmacokinetic Pharmacodynamic Model to Administer Propofol in Obese Patients
NCT01596387 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of Influencing Variables in Awakening Concentration and Concentration at Body Movements of Propofol TCI (Targeted Controlled Infusion) Targeted at the Effector Site
NCT04129112 ·Status: COMPLETED
-
The Influence of Age on Bispectral Index Associated With Propofol-induced Sedation
NCT02046720 ·Status: COMPLETED ·Phase: PHASE3
-
Development of a Pharmacodynamic Model for Propofol in Older Adults
NCT05790720 ·Status: RECRUITING ·Phase: NA
-
Clinical Effect of Two Pharmacokinetics Model of Propofol
NCT02155517 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Age on Propofol-BIS Response
NCT02585284 ·Status: COMPLETED
-
Effect of Intravenous Lidocaine on BIS-guided Propofol Requirements During General Anesthesia
NCT01366300 ·Status: COMPLETED ·Phase: PHASE4
-
Population Pharmacodynamic Modeling of the Sedative and Side Effects of Propofol
NCT02173340 ·Status: COMPLETED
-
Application of the Propofol Precise Infusion Model
NCT05158426 ·Status: COMPLETED
-
Impact of Propofol Reduction in Anesthesia Induction
NCT04194151 ·Status: COMPLETED ·Phase: PHASE4
-
Blood Propofol Measurement During Anaesthesia Using Propofol Target Controlled Infusion
NCT01549639 ·Status: COMPLETED
-
Population Pharmacokinetics and Clinical Individual Dosage Regimen of Propofoll Injection
NCT03422315 ·Status: UNKNOWN ·Phase: NA
-
Bispectral Index (BIS) Values Required for an Adequate Depth of Anesthesia in Elderly Patients Using Propofol
NCT03195530 ·Status: TERMINATED
-
Remifentanil for Preventing Propofol Injection Pain in Elderly Patients
NCT03330782 ·Status: COMPLETED ·Phase: PHASE4
-
Observation on Administration of Propofol at Different Titration Endpoints
NCT06685198 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Sufentanil Bispectral Index Elderly
NCT02831101 ·Status: COMPLETED ·Phase: NA
-
Comparison of Different Propofol Formulations With or Without Remifentanil
NCT01592162 ·Status: COMPLETED ·Phase: PHASE4
-
Hemodynamics During Induction of General Anesthesia With High and Low Propofol Dose.
NCT03861364 ·Status: COMPLETED ·Phase: PHASE4
-
Propofol Pharmacokinetics in Children After Single Bolus Dose
NCT02303223 ·Status: COMPLETED ·Phase: NA