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Onset Time of Thiopental Versus Propofol in the Elderly

NCT00965107 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 78

Last updated 2010-03-09

No results posted yet for this study

Summary

This study is aimed at increasing the safety of the use of anaesthesia in an elderly population (\> 60 years). Patients with decreased physiological reserve, including all elderly patients, have an increased risk of getting an erroneous induction bolus. This project will investigate how fast elderly patients (\> 60 years) fall asleep during bolus induction of anaesthesia with two of the most used hypnotics, thiopental and propofol, evaluated with BIS-monitoring and clinical signs of anaesthetic depth. The hemodynamic response will also be evaluated.

Conditions

  • Induction of Anaesthesia
  • Age

Interventions

DRUG

Thiopental

Thiopental given as a bolus dose of 2,5 mg/kg.

DRUG

Propofol

Propofol given as a bolus dose of 1 mg/kg.

Sponsors & Collaborators

  • TrygFonden, Denmark

    collaborator INDUSTRY

  • Rigshospitalet, Denmark

    lead OTHER

Principal Investigators

  • Lars Rasmussen, MD, PHD · Rigshospitalet, Denmark

  • Martin K Soerensen, MD · Rigshospitalet, Denmark

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-09-30
Primary Completion
2010-03-31
Completion
2010-03-31

Countries

  • Denmark

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00965107 on ClinicalTrials.gov