Effects of Peanut Consumption on Postprandial Inflammation, Glucose and Triglycerides
NCT01173042 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6
Last updated 2023-08-21
Summary
This pilot study will investigate the effects of acute peanut consumption on markers of inflammation, triglycerides and glucose. The hypothesis is that a high glucose/SFA meal will increase postprandial production of the inflammatory marker, C-reactive protein (CRP), and that the addition of peanuts to the control meal will reduce the production of CRP, as well as triglycerides and glucose.
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
Peanuts
Shake containing 3.0oz of peanuts (including skin) + control (heavy whipping cream, glucose and chocolate syrup)
- DIETARY_SUPPLEMENT
-
Glucose and whipping cream
An oral liquid glucose (75g) and fat (high saturated fat from 60g heavy whipping cream) load. Chocolate syrup is added for flavor.
- DIETARY_SUPPLEMENT
-
Oil Blend
Shake containing an oil blend (sunflower, sesame, olive and palm oils) + control (heavy whipping cream, glucose and chocolate syrup). The amount of oil added to the control will provide an equivalent amount of fat to that provided in 3 oz (85g) of peanuts
Sponsors & Collaborators
-
The Peanut Institute
collaborator OTHER -
Penn State University
lead OTHER
Principal Investigators
-
Alison M Hill, Ph.D · Penn State University, Department of Nutritiontal Sciences
-
Penny M. Kris-Etherton, Ph.D · Penn State University, Department of Nutritional Sciences
-
Li Wang · Penn State University, Department of Nutritional Sciences
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- SINGLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 30 Years
- Max Age
- 50 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-08-31
- Primary Completion
- 2010-01-31
- Completion
- 2010-02-28
Countries
- United States
Study Locations
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