Effects of Peanut Consumption on Postprandial Inflammation, Glucose and Triglycerides

NCT01173042 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 6

Last updated 2023-08-21

No results posted yet for this study

Summary

This pilot study will investigate the effects of acute peanut consumption on markers of inflammation, triglycerides and glucose. The hypothesis is that a high glucose/SFA meal will increase postprandial production of the inflammatory marker, C-reactive protein (CRP), and that the addition of peanuts to the control meal will reduce the production of CRP, as well as triglycerides and glucose.

Conditions

Interventions

DIETARY_SUPPLEMENT

Peanuts

Shake containing 3.0oz of peanuts (including skin) + control (heavy whipping cream, glucose and chocolate syrup)

DIETARY_SUPPLEMENT

Glucose and whipping cream

An oral liquid glucose (75g) and fat (high saturated fat from 60g heavy whipping cream) load. Chocolate syrup is added for flavor.

DIETARY_SUPPLEMENT

Oil Blend

Shake containing an oil blend (sunflower, sesame, olive and palm oils) + control (heavy whipping cream, glucose and chocolate syrup). The amount of oil added to the control will provide an equivalent amount of fat to that provided in 3 oz (85g) of peanuts

Sponsors & Collaborators

  • The Peanut Institute

    collaborator OTHER
  • Penn State University

    lead OTHER

Principal Investigators

  • Alison M Hill, Ph.D · Penn State University, Department of Nutritiontal Sciences

  • Penny M. Kris-Etherton, Ph.D · Penn State University, Department of Nutritional Sciences

  • Li Wang · Penn State University, Department of Nutritional Sciences

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
30 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2009-08-31
Primary Completion
2010-01-31
Completion
2010-02-28

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01173042 on ClinicalTrials.gov