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Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients

NCT00429637 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2008-08-07

No results posted yet for this study

Summary

Given the possible prognostic relationship between exhaled breath condensate pH and clinical symptoms, it is quite plausible that exhaled breath condensate pH can prove useful in the intensive care unit. For example, if exhaled breath condensate pH falls prior to the onset of clinical symptoms, it is likely that it can be useful as an early marker, heralding the onset of various inflammatory lung diseases. Specifically, exhaled breath condensate pH could be used as a safe, non-invasive screening tool for Ventilator Associated Pneumonia. Similarly, just as changes in exhaled breath condensate pH might predict the onset of disease, exhaled breath condensate pH changes might also mark the progression or resolution of disease (e.g. alerting clinicians to possible readiness for extubation). Although such notions are hypothetical, they are beginning to be supported by anecdotal evidence.

Conditions

  • Respiratory Distress Syndrome, Adult
  • Respiratory Syncytial Virus Infections
  • Pneumonia
  • Acute Lung Injury

Sponsors & Collaborators

  • University of Virginia

    lead OTHER

Principal Investigators

  • John F Hunt, MD · University of Virginia

Eligibility

Min Age
1 Hour
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2004-12-31
Completion
2009-01-31

Countries

  • United States

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00429637 on ClinicalTrials.gov