Slope of the Pressure-Time Waveform Predicts Resistance and Compliance in Mechanically Ventilated Subjects

NCT00750074 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 12

Last updated 2017-02-28

No results posted yet for this study

Summary

There are two fundamentally different ways to ventilate critically ill patients: constant flow, volume-preset modes (such as volume assist-control) and pressure-preset modes (such as pressure-control and pressure-support). Critically ill patients suffer mechanical derangements of the respiratory system that raise the work of breathing. Knowledge of these mechanical properties is useful diagnostically and as a measure of response to treatment over time. It has been proposed that only constant flow, volume-preset modes are able to offer diagnostic information about the changes in the subject's lungs in terms of resistance and elastance properties. This study proposes to examine if similar information can be extracted from pressure-preset modes by comparing information from both modes of ventilation.

Conditions

  • Respiration Disorders

Sponsors & Collaborators

  • Gregory A. Schmidt

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
99 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2007-11-30
Primary Completion
2009-09-30
Completion
2010-10-31

Countries

  • United States

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00750074 on ClinicalTrials.gov