Combination Chemotherapy in Treating Patients With Previously Untreated Advanced Hodgkin's Lymphoma
NCT00041210 · Status: UNKNOWN · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 850
Last updated 2013-09-20
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating patients who have advanced Hodgkin's lymphoma.
PURPOSE: Randomized phase III trial to compare the effectiveness of two different combination chemotherapy regimens in treating patients who have advanced Hodgkin's lymphoma.
Conditions
Interventions
- BIOLOGICAL
-
bleomycin sulfate
- DRUG
-
ABVD regimen
- DRUG
-
Stanford V regimen
- DRUG
-
dacarbazine
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
mechlorethamine hydrochloride
- DRUG
- DRUG
-
vinblastine sulfate
- DRUG
-
vincristine sulfate
- RADIATION
-
radiation therapy
Sponsors & Collaborators
-
Mount Vernon Cancer Centre at Mount Vernon Hospital
lead OTHER
Principal Investigators
-
Peter J. Hoskin, MD · Mount Vernon Cancer Centre at Mount Vernon Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2001-10-31
Countries
- United Kingdom
Study Locations
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