Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
NCT00002494 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 134
Last updated 2016-07-04
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy and alternating regimens of chemotherapy in treating patients who have non-Hodgkin's lymphoma or acute lymphocytic leukemia.
Conditions
Interventions
- DRUG
- DRUG
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
ifosfamide
- DRUG
-
leucovorin calcium
- DRUG
-
mesna
- DRUG
-
methotrexate
- DRUG
- DRUG
-
therapeutic hydrocortisone
- DRUG
-
vincristine sulfate
- RADIATION
-
low-LET cobalt-60 gamma ray therapy
- RADIATION
-
low-LET photon therapy
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Alliance for Clinical Trials in Oncology
lead OTHER
Principal Investigators
-
Edward Lee, MD · Central Maryland Oncology Center
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 15 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1992-05-31
- Primary Completion
- 2004-03-31
- Completion
- 2006-01-31
Countries
- United States
Study Locations
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