Combination Chemotherapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma
NCT00005867 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 310
Last updated 2013-06-26
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for non-Hodgkin's lymphoma.
PURPOSE: This randomized phase III trial is studying two regimens of combination chemotherapy and comparing how well they work in treating patients with aggressive non-Hodgkin's lymphoma.
Conditions
Interventions
- BIOLOGICAL
-
bleomycin sulfate
- DRUG
-
CHOP regimen
- DRUG
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
mitoxantrone hydrochloride
- DRUG
-
prednisolone
- DRUG
-
vincristine sulfate
Sponsors & Collaborators
-
Lymphoma Trials Office
lead OTHER
Principal Investigators
-
Ruth Pettengell, MD · St. George's Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Max Age
- 59 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-01-31
- Completion
- 2007-08-31
Countries
- United Kingdom
Study Locations
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