Combination Chemotherapy in Treating Patients With Aggressive Non-Hodgkin's Lymphoma

NCT00005867 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 310

Last updated 2013-06-26

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for non-Hodgkin's lymphoma.

PURPOSE: This randomized phase III trial is studying two regimens of combination chemotherapy and comparing how well they work in treating patients with aggressive non-Hodgkin's lymphoma.

Conditions

Interventions

BIOLOGICAL

bleomycin sulfate

DRUG

CHOP regimen

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

mitoxantrone hydrochloride

DRUG

prednisolone

DRUG

vincristine sulfate

Sponsors & Collaborators

  • Lymphoma Trials Office

    lead OTHER

Principal Investigators

  • Ruth Pettengell, MD · St. George's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Min Age
18 Years
Max Age
59 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-01-31
Completion
2007-08-31

Countries

  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00005867 on ClinicalTrials.gov