Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease
NCT00003421 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 800
Last updated 2013-12-04
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for advanced Hodgkin's disease.
PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients with advanced Hodgkin's disease.
Conditions
Interventions
- BIOLOGICAL
-
bleomycin sulfate
- DRUG
-
ABVD regimen
- DRUG
-
chlorambucil
- DRUG
-
dacarbazine
- DRUG
-
doxorubicin hydrochloride
- DRUG
-
etoposide
- DRUG
-
prednisolone
- DRUG
-
procarbazine hydrochloride
- DRUG
-
vinblastine sulfate
- DRUG
-
vincristine sulfate
- RADIATION
-
radiation therapy
Sponsors & Collaborators
- lead OTHER_GOV
Principal Investigators
-
Barry W. Hancock, MD · Cancer Research Centre at Weston Park Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
- Completion
- 2005-11-30
Countries
- United Kingdom
Study Locations
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