Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Disease

NCT00003421 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 800

Last updated 2013-12-04

No results posted yet for this study

Summary

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for advanced Hodgkin's disease.

PURPOSE: Randomized phase III trial to compare different combination chemotherapy regimens in treating patients with advanced Hodgkin's disease.

Conditions

Interventions

BIOLOGICAL

bleomycin sulfate

DRUG

ABVD regimen

DRUG

chlorambucil

DRUG

dacarbazine

DRUG

doxorubicin hydrochloride

DRUG

etoposide

DRUG

prednisolone

DRUG

procarbazine hydrochloride

DRUG

vinblastine sulfate

DRUG

vincristine sulfate

RADIATION

radiation therapy

Sponsors & Collaborators

Principal Investigators

  • Barry W. Hancock, MD · Cancer Research Centre at Weston Park Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
1998-06-30
Completion
2005-11-30

Countries

  • United Kingdom

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00003421 on ClinicalTrials.gov