UK Research and Innovation has announced major changes to grant funding, with pauses and cuts affecting medical, biological and physical research. The uncertainty has raised concern over curiosity-driven research, staffing and the system’s tolerance for failure.
New research challenges the theory that ketamine's psychedelic effects drive its therapeutic benefits for alcohol use disorder. A study of 96 participants found no link between ketamine's psychoactive experiences and improved abstinence rates. The findings suggest other mechanisms, such as brain network alterations, may explain ketamine's effectiveness in treating addiction.
Research communities in the US and UK face funding disruptions as governments demand greater alignment with national priorities. UKRI has paused grant programs while early-career researchers advocate for increased NIH funding.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07339982 |
Supermarket Labelling and Taxation Study |
RECRUITING | NA |
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Anti-CCR9 CAR T Cells for T Cell Leukaemia/Lymphoma |
RECRUITING | PHASE1 |
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Edmond J. Safra Accelerating Clinical Trials in Parkinson's Disease: A Multiarm Multi-stage Platform Trial |
RECRUITING | PHASE3 |
| NCT07103681 |
White Matter Distortion and Dementia Biomarkers in Normal Pressure Hydrocephalus (NPH) |
RECRUITING | |
| NCT06806501 |
Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations |
RECRUITING | |
| NCT06786936 |
Evaluating the Role of IL-17 as an Orchestrator of Peripheral-central Cross Talk in Depressive Symptoms |
RECRUITING | |
| NCT06729606 |
Aviptadil for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial) |
COMPLETED | PHASE3 |
| NCT06729593 |
Remdesivir for Severely Ill Inpatients With COVID-19 (An ACTIV-3b/TESICO Treatment Trial) |
COMPLETED | PHASE3 |
| NCT06678022 |
Use of Unmanned Air Vehicles (Medical Drones) to Overcome Geographical Barriers to Delivery of Anti-Retroviral Therapy and Biological Samples |
RECRUITING | NA |
| NCT06676384 |
Which of the Commonly Available and Approved Drugs in Addition to Standard of Care Can Significantly Improve the Slope of Estimated Glomerular Filtration Rate at Two Years When Compared to Standard of Care Alone in South-Asian Kidney Biopsy-proven Adult (≥18 Years) Primary IgA Nephropathy? |
RECRUITING | PHASE4 |
