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FABP4 Response After Roux-en-Y Gastric Bypass

NCT07774208 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 28

Last updated 2026-08-19

No results posted yet for this study

Summary

This retrospective observational cohort study examined serum fatty acid-binding protein 4 (FABP4) dynamics in 28 adults who underwent Roux-en-Y gastric bypass (RYGB), followed at baseline, 3 months, and 6 months. Anthropometric, metabolic, and inflammatory parameters were assessed alongside FABP4, fasting GLP-1, and PYY. Patients were classified as FABP4 responders (decrease from baseline to 6 months) or rebound/non-responders. The study investigated whether FABP4 trajectory after RYGB is associated with the magnitude of weight loss, systemic inflammation, and fasting incretin change.

Conditions

  • Obesity (BMI>30)
  • Obesity (BMI > 35)
  • Insulin Resistance
  • Bariatric Surgery
  • Bariatric Surgery (Gastric Bypass)

Sponsors & Collaborators

  • Istanbul University

    lead OTHER

Principal Investigators

  • Bedia Fulya Calikoglu, M.D., PhD. · Istanbul University, Istanbul Medical Faculty

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-04-22
Primary Completion
2014-12-05
Completion
2015-02-10

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07774208 on ClinicalTrials.gov