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Bariatric Surgery And Adipose Inflammation Dysfunction and Type 2 Diabetes Mellitus

NCT01882036 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 57

Last updated 2023-02-14

No results posted yet for this study

Summary

The focus of this proposal is to define the mechanism by which bariatric surgery acutely improves insulin sensitivity. Our central hypothesis is that drastically reduced caloric intake early after Bariatric surgery improves the pro-inflammatory profile of macrophages, which in turn improves insulin sensitivity and glucose homeostasis.

Conditions

Interventions

PROCEDURE

Gastric Bypass w/ matched hypocaloric diet

Roux en Y Gastric Bypass with Hypocaloric liquid diet for 10 days

OTHER

Hypocaloric diet

Hypocaloric liquid diet for 10 days

Sponsors & Collaborators

Principal Investigators

  • Sayeed Ikramuddin, MD · University of Minnesota

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2011-11-30
Primary Completion
2018-07-10
Completion
2018-07-10

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT01882036 on ClinicalTrials.gov