MedTrace Logo

Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System

NCT07753681 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 2084

Last updated 2026-08-07

No results posted yet for this study

Summary

Cognizant of the prevalence of complicated non communicable diseases (NCD) and the attendant capacity problems faced by the health workers in primary care settings, we propose to adapt and pilot the Package of Essential Non-communicable Diseases (PEN) Plus intervention using the Interactive Systems Framework (ISF) and then implement and monitor the impact. The ISF framework proposes and organizes several implementation strategies to achieve Evidence Based Implementation (EBI) adaptation. We will apply these strategies at 2 first level hospitals (Peri-Urban and Rural) to ensure local adaptation and work towards scaling up of the WHO-PEN Plus in the rest of Zambia. This process will be inclusive, involving a Stakeholder Consultation Group that shall include the Zambian Non-Communicable diseases and injuries (NCDI) Poverty Commission and shall report bi-annually to a Project Advisory Board (PAB) chaired by the Permanent Secretary of the Ministry of Health.

Conditions

Interventions

COMBINATION_PRODUCT

Supportive treatment

Buffering of drugs and or equipment to the MOH to ensure that HCWs are able to manage the patients that attend the NCD clinics set up within the first level hospitals.

Sponsors & Collaborators

  • The Leona M. and Harry B. Helmsley Charitable Trust

    collaborator OTHER

  • Centre for Infectious Disease Research in Zambia

    lead OTHER

Principal Investigators

  • Fastone Mathew Goma, MB ChB · Centre for Infectious Disease Research in Zambia

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-08
Primary Completion
2027-09-30
Completion
2027-09-30

Countries

  • Zambia

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07753681 on ClinicalTrials.gov