The global CNS therapeutics market was valued at USD 127.29 billion in 2025 and is projected to reach USD 285.72 billion by 2035, driven by demand for Alzheimer’s and Parkinson’s treatments. North America held 45% of the market; neurodegenerative diseases were the largest segment. Private investment and trends toward biologics and AI are shaping the sector.
A longitudinal study of 460,000 teenagers found that adolescent cannabis use increases the risk of developing bipolar and psychotic disorders by twofold, as well as raising risks for depression and anxiety.
Healthcare systems worldwide are addressing polypharmacy as a major public health issue, with new guidance emphasizing person-centered medication reviews and risk mitigation strategies across multiple clinical settings including infectious disease care.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07753681 |
Domestication and Implementation of the PEN-Plus Clinical Model in the Zambian Health System |
RECRUITING | |
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Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children |
NOT_YET_RECRUITING | NA |
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The Implementation of a Trans-tailored Harm Reduction Service for Transgender Persons in Relation to chemsEX and Substance Use (iT-REX) |
RECRUITING | NA |
| NCT07395700 |
Validation of the Behavioral Activation for Depression Scale in Individuals With Substance Use Disorders |
COMPLETED | |
| NCT07364799 |
Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth |
RECRUITING | NA |
| NCT07336537 |
Evaluating the Acceptability, Feasibility and Usability of Various Conversational Data Collection Software |
RECRUITING | NA |
| NCT07106879 |
Non-interventional Pre-screening Protocol Aims to Evaluate Participants for Potential Trial Eligibility in Future Clinical Trials/Studies Focusing on Metabolic and Psychiatric Health. |
RECRUITING | |
| NCT07098260 |
DECIDE to Improve Maternal Mental Health Care Delivery |
RECRUITING | NA |
| NCT06702332 |
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COMPLETED | PHASE1 |
| NCT05713695 |
Supporting Treatment Access and Recovery Through Linkage and Support |
ACTIVE_NOT_RECRUITING | NA |
