A study from the University of Osaka identified the integrin αV–YAP–CTGF pathway linking chronic liver congestion to fibrosis. The findings point to a potential therapeutic target in congestion-related liver disease.
The European Commission approved Enflonsia for prevention of RSV lower respiratory tract disease in infants during their first RSV season. Merck also reported new Phase 3 SMART data showing generally consistent second-season safety in high-risk children under 2 years old.
Merck announced positive second RSV season findings from the Phase 3 SMART trial evaluating ENFLONSIA (clesrovimab) in infants and children under 2 years at increased risk for severe RSV disease, showing consistent safety and antibody levels similar to healthy infants.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
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Exergame-Based Physical Activity Promotion for Children and Adolescents With Congenital Heart Disease |
NOT_YET_RECRUITING | NA |
| NCT07575451 |
Empowering Families in Pediatric Cardiovascular Surgery: A RAM-Based Approach |
NOT_YET_RECRUITING | NA |
| NCT07574931 |
Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases |
COMPLETED | |
| NCT07559253 |
Implementation of an Accessible Healthcare Model (ACHD STRONG): Comparing Nurse and Physician Lead Healthcare Transition Education in a RE-AIM Framework |
RECRUITING | NA |
| NCT07552688 |
"Effects of High-Calorie Diets VS High-Calorie Formulas on Weight Gain in Children With Congenital Heart Disease " |
NOT_YET_RECRUITING | NA |
| NCT07486167 |
Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07118124 |
Pediatric Adhesion and New Dermal Approach Study |
COMPLETED | NA |
| NCT07115108 |
Effectiveness of High-Energy Density Enteral Nutrition for Enhancing Physical Growth and Cognitive Brain Development in Infants With Congenital Heart Disease |
RECRUITING | NA |
| NCT07114718 |
Starlight Cardiovascular Lifeline Ductus Arteriosus Stent IDE Study |
RECRUITING | NA |
| NCT06833320 |
Propranolol Treatment for Postoperative Chylothorax |
SUSPENDED | PHASE1/PHASE2 |
