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Alleviation of Hypercholesterolemia Through Newly Developed Cookies Supplementedwithpumpkin (Cucurbita Pepo L.) Seeds and Walnuts (Juglans Regia L.) Among Arthrosclerosispatients.

NCT07737067 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 25

Last updated 2026-07-30

No results posted yet for this study

Summary

This study is being conducted at DHQ Hospital, Jhang, under the supervision of the University of Lahore. The purpose of the trial is to find out whether specially prepared cookies made with pumpkin seeds (Cucurbita pepo L.) and walnuts (Juglans regia L.) can help improve cholesterol levels in patients with atherosclerosis.

High cholesterol is one of the major causes of heart disease and stroke. Although medicines are commonly prescribed, adding natural foods with proven health benefits may help patients manage cholesterol in a safer and more affordable way. Pumpkin seeds contain healthy fats, antioxidants, and phytosterols, while walnuts provide omega-3 fatty acids, fiber, and vitamins. Together, they may improve heart health by lowering harmful cholesterol (LDL) and increasing good cholesterol (HDL).

In this study, patients will be divided into two groups:

Treatment group: Will receive one 100 g cookie made with pumpkin seeds and walnuts every day, in addition to their usual care.

Control group: Will receive usual care without the supplemented cookies.

Blood samples will be taken at the start, at 3 weeks, and at 6 weeks to measure cholesterol, triglycerides, LDL, and HDL levels. Researchers will follow up with participants regularly to ensure safety and compliance.

The study will help determine whether these cookies can be recommended as a natural, food-based approach to reducing cholesterol and preventing complications of heart disease.

Conditions

Interventions

DIETARY_SUPPLEMENT

Pumpkin Seed and Walnut Cookies

Participants in the intervention group will consume 100 g of cookies supplemented with pumpkin seeds (Cucurbita pepo L.) and walnuts (Juglans regia L.) once daily for 6 weeks. The cookies are prepared with standardized ingredients including whole wheat flour, roasted pumpkin seeds, roasted walnuts, butter, sugar, milk, and baking powder. The supplementation is designed to provide a rich source of polyunsaturated fatty acids, dietary fiber, phytosterols, vitamins, and minerals to support improvement in lipid profile and cardiovascular health.

OTHER

Standard Care (Control)

Participants in the control group will receive conventional medical treatment for hypercholesterolemia and atherosclerosis as prescribed by their physician. No dietary supplementation will be provided.

Sponsors & Collaborators

  • University of Lahore

    collaborator OTHER

  • Kamran Hanif

    lead OTHER

Principal Investigators

  • Kamran Hanif, Phd · University of Lahore

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
25 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-09-15
Primary Completion
2025-10-06
Completion
2025-10-15

Countries

  • Pakistan

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07737067 on ClinicalTrials.gov