Pumpkin Seeds or Oil Lower Serum Triglyceride Levels in Individuals With Hyperlipidaemia
NCT07123844 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 159
Last updated 2025-08-14
Summary
Aim of the Study:
This randomized controlled experimental study aimed to evaluate the effects of cholesterol-restricted diets enriched with pumpkin seeds and pumpkin seed oil on cardiovascular risk factors-specifically serum lipid profile (total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides), blood pressure, and anthropometric measurements (body weight, body mass index, body fat percentage, and fat mass)-in individuals with hyperlipidemia.
Research Questions:
Does the nutritional intervention lead to a reduction in serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels, as well as an increase in high-density lipoprotein cholesterol (HDL-C) levels across all study groups?
Do the groups receiving diets enriched with pumpkin seeds or pumpkin seed oil show greater improvements in lipid profile (TC, LDL-C, TG) and a more pronounced increase in HDL-C compared to the control group?
Does the nutritional intervention result in reductions in body weight, BMI, body fat percentage, and fat mass in all study groups?
Conditions
Interventions
- DIETARY_SUPPLEMENT
-
low cholesterol diet
low cholesterol diet
Sponsors & Collaborators
-
Okan University
collaborator OTHER -
Kastamonu University
lead OTHER
Principal Investigators
-
Hande Öngün Yılmaz, pHD · [email protected]
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 19 Years
- Max Age
- 64 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-06-01
- Primary Completion
- 2023-09-30
- Completion
- 2023-11-03
Countries
- Turkey (Türkiye)
Study Locations
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