Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry
NCT07732686 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000
Last updated 2026-07-29
Summary
The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.
Conditions
- Pancreas Cancer
- Hepatocellular Carcinoma
- Lung Cancer
- Ovarian Cancer
- Breast Cancer
- Head and Neck Cancer
- Colon Cancer
- Bladder Cancer
- Other Cancer
Interventions
- DEVICE
-
Proton Transfer Reaction Mass Spectrometry Analysis
This is a noninvasive intervention. Participants will be asked to provide a breath sample using a disposable mouthpiece equipped with a saliva/moisture trap and a non-rebreathing valve. Breath samples will be collected through normal, steady exhalation. The entire breath collection process is expected to take no more than 30 minutes to complete.
Sponsors & Collaborators
-
University of Oklahoma
lead OTHER
Principal Investigators
-
Nirmal Choradia, MD · University of Oklahoma - Stephenson Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2026-10-31
- Primary Completion
- 2027-10-31
- Completion
- 2029-10-31
Countries
- United States
Study Locations
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