Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry

NCT07732686 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 2000

Last updated 2026-07-29

No results posted yet for this study

Summary

The purpose of this clinical trial is to evaluate whether volatile organic compound (VOC) signatures detected in the breath of patients with cancer can serve as a potential screening tool for the early detection of cancer.

Conditions

Interventions

DEVICE

Proton Transfer Reaction Mass Spectrometry Analysis

This is a noninvasive intervention. Participants will be asked to provide a breath sample using a disposable mouthpiece equipped with a saliva/moisture trap and a non-rebreathing valve. Breath samples will be collected through normal, steady exhalation. The entire breath collection process is expected to take no more than 30 minutes to complete.

Sponsors & Collaborators

  • University of Oklahoma

    lead OTHER

Principal Investigators

  • Nirmal Choradia, MD · University of Oklahoma - Stephenson Cancer Center

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-10-31
Primary Completion
2027-10-31
Completion
2029-10-31

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07732686 on ClinicalTrials.gov