Lung cancer is a malignant disease that starts in lung tissue and includes two major classes: non-small cell lung cancer and small cell lung cancer. It remains one of the leading causes of cancer morbidity and mortality.
Senticell closed an oversubscribed seed round of nearly $7 million to advance its red blood cell-based liquid biopsy platform. The company is running two clinical studies at Penn Medicine enrolling about 300 patients to compare its RBC signal against plasma-based tests.
Moderna and Merck's personalized mRNA cancer vaccine, intismeran autogene, showed promising Phase 3 results in preventing melanoma recurrence. Combined with Keytruda, it cut recurrence risk by half and reduced spread by 59% in earlier data. The treatment could reach patients within two years pending regulatory approval.
AbbVie will present new lung cancer data at WCLC 2026, including Phase 1b results for ABBV-1480 showing high response rates in NSCLC and safety updates for ABBV-706 in SCLC. The company also reported progress in dermatology, obesity, and Crohn's disease programs.
IceCure Medical's ProSense cryoablation system gains IRB approval for the ChoICE post-marketing study in low-risk breast cancer, with patient enrollment expected soon. Additionally, Thomas Hospital in Alabama becomes the first facility in the state to install ProSense, with procedures starting this month.
Merck and Moderna's personalized mRNA cancer vaccine combined with Keytruda significantly reduced melanoma recurrence risk in a Phase 3 trial. The FDA has not yet approved the vaccine, with potential availability expected by early 2027.
A Chest study finds that respiratory or red flag symptoms at baseline increase the likelihood of lung cancer diagnosis within one year after screening. A Nature study identifies glucocorticoid-related genes with causal links to non-small cell lung cancer and constructs a multi-omics prognostic model.
Michelle, a mental health therapist, was diagnosed with stage 4 lung cancer and given 24 months to live. Through yoga and meditation, she shifted her mindset and is now thriving six years after diagnosis, with tumors continuing to shrink.
Johnson & Johnson agreed to buy Firefly Bio for $1 billion to advance KRAS-targeted cancer therapies. The company also announced a $1 billion cell therapy manufacturing plant in Pennsylvania as part of a $55 billion US investment plan.
A first-in-human T-cell therapy showed lasting benefit in children with DIPG and relapsed CNS tumors, while a preclinical mRNA vaccine reduced neuroblastoma tumor size by 70%. Aneuploidy predicted response to olaparib plus irinotecan.
Clinical trials show a pancreatic cancer drug nearly doubles survival, a head-and-neck therapy shrinks tumors, and new research explains drug resistance. Cancer mortality is falling in the US and UK.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07816263 |
Guaraná Supplementation for Cancer-Related Fatigue |
RECRUITING | |
| NCT07808164 |
ENPP1/cGAS (EG) and FAP Expression Profiles in Solid Tumors: An Immunohistochemical Study in a Vietnamese Cohort |
RECRUITING | |
| NCT07807696 |
Olive Oil Before Lung Cancer Surgery to Prevent Chylothorax |
RECRUITING | NA |
| NCT07804017 |
Exhaled Breath Electronic Nose for Multi-Disease Risk Prescreening |
NOT_YET_RECRUITING | |
| NCT07802847 |
Innovative and Cooperative Pathway Integrating Oncogeriatric, Pharmaceutical and Pharmacological Follow-up in Elderly Patients. |
NOT_YET_RECRUITING | PHASE4 |
| NCT07795411 |
Prospective Multiomic Analysis in Small-Cell Lung Cancer |
NOT_YET_RECRUITING | |
| NCT07792824 |
Witness Project Lung |
NOT_YET_RECRUITING | NA |
| NCT07788729 |
Social Prescriptions and Micro-Learning to Improve Care for Cancer Patients and Their Support Persons |
RECRUITING | NA |
| NCT07785791 |
ERAS Compliance and Nutritional Outcomes After Lung Cancer Surgery |
RECRUITING | |
| NCT07782359 |
Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib |
NOT_YET_RECRUITING | PHASE1 |
