Metabolomic and Epigenetic Profiling of Bodyfluids From Lung and Brain Cancer Receiving Radiation Therapy
NCT02259218 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 273
Last updated 2026-04-13
Summary
This research trial studies metabolomic and other molecular profiling to identify predictive biomarkers for radiation toxicity and survival in patients with lung or brain cancers receiving radiation therapy. Studying samples of blood, urine, and tissue from patients with lung or brain cancer in the laboratory may help doctors identify and learn more about biomarkers related to cancer and predict which patients are at higher risk for developing radiation side effects and how well patients will respond to radiation treatment.
Conditions
- Adult Brain Tumor
- Lung Cancer
- Radiation Toxicity
Interventions
- OTHER
-
laboratory biomarker analysis
Correlative studies
Sponsors & Collaborators
-
Ohio State University Comprehensive Cancer Center
lead OTHER
Principal Investigators
-
Arnab Chakravarti, MD · Ohio State University Comprehensive Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-10-04
- Primary Completion
- 2025-09-17
- Completion
- 2025-09-17
Countries
- United States
Study Locations
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