MedTrace Logo

Intravenous Anesthesıa and Cognıtıve Functıon ın Spınal Surgery

NCT07701187 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 128

Last updated 2026-07-14

No results posted yet for this study

Summary

The aim of this study is to investigate the effect of these two different intravenous infusion techniques \[manuel controlled infusion (MCI) and Target controlled Infusion( TCI)\] on POCD. To assess POCD, the Mini Mental State Examination (MMSE ) and the Montreal Cognitive Assessment (MoCA ) will be used. MoCA and MMSE have high sensitivity and specificity for identifying patients with mild cognitive impairment who perform within the normal range. In a study by Meng et al., comparing target-controlled infusion and manual infusion of propofol anesthesia during electroconvulsive therapy, the randomized, controlled trial showed no significant difference in postelectroconvulsive therapy changes in MoCA scores in either group; however, they reported improvement in MoCA scores after 6 electroconvulsive therapy treatments in the MCI group, while deterioration occurred in the TCI group. Researchers found no studies investigating the effects of both infusion methods in spinal surgery and their impact on cognitive function, and they planned to evaluate the effects of the groups in their study.

Conditions

  • Postoperative Cognitive Dysfunction (POCD)

Interventions

DEVICE

Manuel controlled infusion group

infusion via manually controlled infusion pumps

Sponsors & Collaborators

  • Bursa Yuksek Ihtisas Training and Research Hospital

    lead OTHER_GOV

Study Design

Allocation
NA
Purpose
PREVENTION
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2023-09-22
Primary Completion
2024-09-22
Completion
2024-09-22

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07701187 on ClinicalTrials.gov