Minimal-flow Anesthesia and Cognitive Outcomes in Elderly Surgical Patients
NCT07424729 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2026-03-18
Summary
Purpose:
Postoperative cognitive dysfunction (POCD) is a common complication in elderly patients following major surgery and is associated with impaired attention, memory, and executive functions. Advanced age and prolonged surgical duration are among the most important risk factors. Minimal flow anesthesia has been suggested to reduce postoperative cognitive impairment by providing more stable anesthetic depth and reducing physiological stress.
The aim of this study is to investigate the relationship between surgical duration and postoperative cognitive dysfunction in elderly patients undergoing surgery under minimal flow anesthesia.
Conditions
- Postoperative Cognitive Dysfunction
Interventions
- OTHER
-
Mini-Mental State Examination
Cognitive function will be assessed using the Mini-Mental State Examination preoperatively and at postoperative time points.
Sponsors & Collaborators
-
Ankara Etlik City Hospital
lead OTHER_GOV
Principal Investigators
-
oya çimen, MD · Ankara Etlik City Hospital
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- OTHER
- Masking
- SINGLE
- Model
- PARALLEL
Eligibility
- Min Age
- 65 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-10-03
- Primary Completion
- 2026-03-12
- Completion
- 2026-03-15
Countries
- Turkey (Türkiye)
Study Locations
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