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Cognitive Functions on Coronary Surgery

NCT04725708 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2023-03-29

No results posted yet for this study

Summary

The aim of this study is to examine the effects of different but safe levels of arterial oxygen levels used in cardiac surgeries on cerebral oxygenation during the operation. It is also to investigate the effect on cognitive functions in the postoperative period. For our study the investigators will conduct a randomized control trial. Patients will be randomly assigned to one of two possible study groups according to the arterial oxygen levels.If there is any abnormality in cerebral oxygen levels during surgery, necessary intervention will be made by doctors.

Conditions

  • Neurocognitive Disorders

Interventions

PROCEDURE

procedure: cerebral oxygenation intervention

During the surgery, cerebral oxygenation will be followed and intervention will be made to pH, PaO2, PaCO2, mean arterial pressure, hematocrit when necessary. In addition perfusion flow was maintained at or close to between 2.2-2.5 L/min/m2 . Perfusion pressure was adjusted using a phenylephrine infusion to maintain a mean arterial pressure of 50 to 70 mm Hg.

Sponsors & Collaborators

  • Bursa Yuksek Ihtisas Training and Research Hospital

    lead OTHER_GOV

Principal Investigators

  • Tuğba T ONUR, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Ümran Ü KARACA, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Filiz F ATA, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Halil Erkan H SAYAN, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Anıl A ONUR, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Canan C YILMAZ, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Ayşe Neslihan AN BALKAYA, MD · Bursa Yuksek Ihtisas Training and Research Hospital

  • Cüneyt C ERİŞ · Bursa Yuksek Ihtisas Training and Research Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-11-01
Primary Completion
2020-05-01
Completion
2020-08-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04725708 on ClinicalTrials.gov