Effects of General Anesthesia on Brain FC and Cognition in Children With Potential Neurological Damage

NCT05602311 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2022-11-15

No results posted yet for this study

Summary

Postoperative Cognitive Dysfunction(POCD)is a common postoperative complications, existing clinical research focused on the adult patients, ignoring that the developing human brain with underlying neurological impairments may be at higher risk for cognitive impairment, so we need a prospective study, observe this kind of "special groups" in the brain structure and function of before and after general anesthesia, To determine the susceptibility to neurotoxicity of general anesthesia drugs.

Conditions

  • Postoperative Cognitive Dysfunction

Interventions

DRUG

General anesthetic

Monitoring the changes of brain functional connectivity and assess cognition in two groups after general anesthesia

Sponsors & Collaborators

  • Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

    lead OTHER

Principal Investigators

  • lai jiang, Dr. · Xinhua Hospital Affiliated to Shanghai Jiao Tong University

Eligibility

Min Age
4 Years
Max Age
10 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-08-15
Primary Completion
2023-01-01
Completion
2023-02-15

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05602311 on ClinicalTrials.gov