Effects of General Anesthesia on Brain FC and Cognition in Children With Potential Neurological Damage
NCT05602311 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 120
Last updated 2022-11-15
Summary
Postoperative Cognitive Dysfunction(POCD)is a common postoperative complications, existing clinical research focused on the adult patients, ignoring that the developing human brain with underlying neurological impairments may be at higher risk for cognitive impairment, so we need a prospective study, observe this kind of "special groups" in the brain structure and function of before and after general anesthesia, To determine the susceptibility to neurotoxicity of general anesthesia drugs.
Conditions
- Postoperative Cognitive Dysfunction
Interventions
- DRUG
-
General anesthetic
Monitoring the changes of brain functional connectivity and assess cognition in two groups after general anesthesia
Sponsors & Collaborators
-
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
lead OTHER
Principal Investigators
-
lai jiang, Dr. · Xinhua Hospital Affiliated to Shanghai Jiao Tong University
Eligibility
- Min Age
- 4 Years
- Max Age
- 10 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2022-08-15
- Primary Completion
- 2023-01-01
- Completion
- 2023-02-15
Countries
- China
Study Locations
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