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Incidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment

NCT07135336 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 340

Last updated 2025-08-22

No results posted yet for this study

Summary

This study aims to find out how often memory and thinking problems happen after surgery in people who already have memory issues before their operation. These memory problems are called postoperative cognitive decline (POCD). Older adults with memory problems before surgery may be more likely to have trouble with thinking, memory, and daily activities after their operation. This study will follow patients who already have memory problems before surgery and see how their thinking and memory change after surgery. The results will help doctors better understand how to care for these patients before, during, and after surgery.

Conditions

  • Cognitive and Behavioral Impairment

Interventions

PROCEDURE

surgery

Patients with preexisting cognitive impairment undergoing elective non-cardiac surgery under general anesthesia.

OTHER

norma

Cognitively normal individuals who do not undergo surgery but complete the same cognitive assessments at baseline, 3 months, and 12 months for normative reference.

Sponsors & Collaborators

  • Peking University Shenzhen Hospital

    lead OTHER

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-07-15
Primary Completion
2027-01-01
Completion
2027-07-01

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07135336 on ClinicalTrials.gov