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Senescence in Myocardial Infarction

NCT07693712 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 22

Last updated 2026-07-09

No results posted yet for this study

Summary

The investigators of this study have found that after a heart attack, some heart cells rapidly age (become senescent) and release proteins that make the heart disease worse.

The investigators of this study would like to check for these aged-cell proteins in participants who have coronary artery bypass graft (CABG) surgery after a recent heart attack or to treat more stable heart disease.

The investigators will do this by taking blood samples and a sample of normally discarded heart tissue from each group of participants. This might help tell us who is at the highest risk of developing heart disease and how people recover from a heart attack.

Conditions

Sponsors & Collaborators

  • Newcastle University

    collaborator OTHER

  • South Tees Hospitals NHS Foundation Trust

    lead OTHER

Principal Investigators

  • Gavin Richardson · Newcastle University

  • Enoch Akowuah · South Tees Hospitals NHS Foundation Trust

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-05-08
Primary Completion
2026-02-26
Completion
2026-02-26

Countries

  • United Kingdom

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07693712 on ClinicalTrials.gov