Study Of Factors Favoring The Onset Of Novo Atrial Fibrillation In The Immediate Aftermath Of Coronary Artery Bypass Surgery
NCT02042547 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100
Last updated 2014-01-23
Summary
Before la surgery:
Transthoracic cardiac echography will be done systematically, to measure among other things the size of the left atrium.
During surgery:
Surgery under extracorporeal circulation: tissue samples will be harvested from the right atrium (one before clamping of the aorta (T0= pre-ischemia sample), immediately before declamping of the aorta (T1= post-ischemia sample).
Surgery without extracorporeal circulation: tissue samples from the right atrium before CABG (T0) and a second sample after CABG (T1).
In parallel with the harvesting of cardiac tissue, blood samples will be taken at different times (H0, H3, H24) to correlate tissue data with systemic data. These will be taken by the anesthetists.
After the surgery:
Holter ECG will be set up for 7 days of continuous recording. Each patient will fill in an observation notebook. The biological samples will be analysed immediately and the biological data obtained will be recorded in the observation notebook.
Conditions
- Coronary Artery Bypass Graft With or Without ECC
Interventions
- OTHER
-
Tissue samples from the right atrium
- OTHER
-
Blood samples
Sponsors & Collaborators
-
Centre Hospitalier Universitaire Dijon
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 79 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2010-09-30
- Primary Completion
- 2013-09-30
Countries
- France
Study Locations
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