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One-Month DAPT in CABG Patients

NCT05997693 · Status: RECRUITING · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 700

Last updated 2025-12-22

No results posted yet for this study

Summary

The purpose of this study is to compare the effect of ticagrelor plus low-dose aspirin versus low-dose aspirin alone in patients with chronic coronary disease undergoing coronary artery bypass grafting.

Conditions

  • Chronic Coronary Disease

Interventions

DRUG

Ticagrelor 90 MG

Ticagrelor 90 mg twice daily taken orally for one month

DRUG

Low-dose aspirin

75-150 mg once daily taken orally

Sponsors & Collaborators

  • Canadian Institutes of Health Research (CIHR)

    collaborator OTHER_GOV

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Marc Ruel, MD, MPH · Ottawa Heart Institute Research Corporation

  • Mario Gaudino, MD, PhD, MSCE · Weill Medical College of Cornell University

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2024-08-15
Primary Completion
2027-01-31
Completion
2031-01-31
FDA Drug
Yes

Countries

  • United States
  • Austria
  • Canada
  • China
  • Germany
  • Sweden

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05997693 on ClinicalTrials.gov