MedTrace Logo

RESISTANCE TRAINING AND CAPILLARIZATION - ROLE ON THE ANABOLIC RESPONSE IN OLDER ADULTS

NCT07680036 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2026-07-07

No results posted yet for this study

Summary

The goal of this clinical trial is to learn how muscle capillaries influence the response to resistance exercise training in older adults. The study will include older men and women who may experience age-related declines in muscle mass and function. The main questions it aims to answer are:

* Does baseline muscle capillarization influence the increase in muscle size and function following resistance exercise training?
* Can resistance exercise stimulate the formation of new capillaries in older adults with lower baseline capillarization, and how is this related to muscle growth?

Participants will:

* Undergo assessments of muscle structure, capillarization, and physical function before and after the intervention.
* Participate in a supervised resistance exercise training program.
* Provide muscle samples and other physiological measurements to evaluate changes in muscle growth and blood vessel formation.

Researchers will analyze the relationship between baseline muscle capillarization, exercise-induced angiogenesis, and improvements in muscle mass and function to better understand why some older adults respond more effectively to resistance exercise than others.

Conditions

  • Older Adults (65 Years and Older)

Interventions

OTHER

Exercise

2 months of different combination of aerobic and resistance training before undergoing to 1 month of resistance training at 80% 1RM

Sponsors & Collaborators

  • University of Padova

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-01
Primary Completion
2025-12-31
Completion
2026-05-31

Countries

  • Italy

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07680036 on ClinicalTrials.gov