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Gas6 and Soluble MerTK in Periodontal Diseases

NCT07535177 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 90

Last updated 2026-04-16

No results posted yet for this study

Summary

This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.

Conditions

  • Periodontitis

Interventions

OTHER

gingival crevicular fluid collection

Gingival crevicular fluid collection using sterile paper strips inserted into the gingival sulcus for 30 seconds from selected periodontal sites (healthy, gingivitis, and periodontitis) for biomarker analysis (Gas6 and sMerTK).

Sponsors & Collaborators

  • Abant Izzet Baysal University

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2026-03-25
Primary Completion
2026-05-10
Completion
2026-05-20

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07535177 on ClinicalTrials.gov