MedTrace Logo

Oral and Systemic Levels of TFF-1 and TTF-3 in Periodontal Diseases

NCT04407026 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 100

Last updated 2020-05-29

No results posted yet for this study

Summary

Trefoil factor family (TFF) consists of a group of small peptides that have key roles in host immune response and repair of tissue damage. Interleukin (IL)-1β is a regulatory proinflammatory cytokine in periodontal inflammation. This study aimed to investigate the levels of TFF-1, TFF-3 and IL-1β in gingival crevicular fluid (GCF), saliva and serum of patients with gingivitis, stage 3 periodontitis and healthy individuals.

Conditions

  • Periodontal Diseases

Interventions

BIOLOGICAL

biofluids

Gingival crevicular fluid, saliva and serum samples were obtained.

Sponsors & Collaborators

  • Aydin Adnan Menderes University

    lead OTHER

Principal Investigators

  • Zeynep Pinar Keles Yucel · Giresun University

Eligibility

Min Age
25 Years
Max Age
49 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-07-01
Primary Completion
2018-03-01
Completion
2018-04-01

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04407026 on ClinicalTrials.gov