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GCF and Saliva Levels of IL-36α in Periodontal Disease

NCT07497828 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 80

Last updated 2026-03-27

No results posted yet for this study

Summary

Interleukin-36 (IL-36), recently identified and members of the IL-1 family, have been reported to be important regulators of host defense against pathogens in the oral mucosa. The aim of this study was to investigate the levels of IL-36 alpha (α) in saliva and gingival crevicular fluid (GCF) of patients with periodontitis, gingivitis and periodontally healthy individuals and to compare these levels with clinical parameters.

Conditions

  • Periodontal Diseases
  • Saliva
  • Gingival Crevicular Fluid
  • Cytokine

Interventions

DIAGNOSTIC_TEST

Collection of fluid samples

Collection of Gingival crevicular fluid and saliva from all patients at baseline.

Sponsors & Collaborators

  • Ordu University

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2023-12-10
Primary Completion
2025-01-10
Completion
2025-01-10

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07497828 on ClinicalTrials.gov