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Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment

NCT07491627 · Status: ENROLLING_BY_INVITATION · Phase: NA · Type: INTERVENTIONAL · Enrollment: 56

Last updated 2026-04-22

No results posted yet for this study

Summary

Impact of nicotine gingival intoxication on the clinical outcomes after periodontitis non surgical treatment

Conditions

  • Periodontitis
  • Smoking Cessation
  • Tobacco Dependence

Interventions

PROCEDURE

periodontal non-surgical treatment

The procedure will consist of non-surgical periodontal treatment (NSPT), consisting of the removal of supra- and subgingival plaque using ultrasonic instruments. Prior to the NSPT, all unstimulated saliva will be collected using Eppendorf. During local anesthesia for the NSPT, a gingival tissue biopsy will be performed using a 2mm wide and 4mm deep punch in the maxillary retromolar area behind the last tooth in the arch.

Sponsors & Collaborators

  • University of Liege

    lead OTHER

Study Design

Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-01-06
Primary Completion
2029-06-30
Completion
2029-06-30

Countries

  • Belgium

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07491627 on ClinicalTrials.gov