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Periodontal Pathogens and Atherom Plaque The Number of Mitochondrial DNA Copies

NCT07165054 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 51

Last updated 2026-01-30

No results posted yet for this study

Summary

Periodontitis is a chronic inflammatory disease of the tooth-supporting tissues characterized by the constant interaction of microorganisms in subgingival plaque and host defense mechanisms. Periodontitis is considered a focus of infection caused by oral bacteria, bacterial byproducts, or inflammatory mediators that can interact with other parts of the body via the bloodstream.

Conditions

  • Periodontal Inflammation
  • Biofilm
  • Endothelial Dysfunction
  • Oral Bacteria

Interventions

OTHER

atheroma plaque

Before the endarterectomy procedure, samples will be collected for study from some of the atheroma plaques routinely taken for pathology from patients.

OTHER

Dental plaque

Subgingival plaque samples will be collected from patients before the endarterectomy procedure.

Sponsors & Collaborators

  • Istanbul Saglik Bilimleri University

    lead OTHER

Eligibility

Min Age
25 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2025-04-10
Primary Completion
2025-11-01
Completion
2025-12-01

Countries

  • Turkey (Türkiye)

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07165054 on ClinicalTrials.gov