MedTrace Logo

Evaluation of Trimethylamine N-oxide (TMAO) Levels in Periodontal Disease

NCT06906510 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 48

Last updated 2025-04-02

No results posted yet for this study

Summary

Salivary and serum levels of TMAO and TNF-α can distinguish between individuals with periodontitis and periodontally healthy individuals.

Conditions

  • Periodontitis
  • Inflammation
  • Trimethylamine N-oxide (TMAO)
  • TNF-alfa

Interventions

DIAGNOSTIC_TEST

Salivary and Serum TMAO Mesurement

Salivary and serum TMAO levels were measured by liquid chromatography-mass spectrometry (LC-MS/MS)

DIAGNOSTIC_TEST

Salivary and Serum TNF-α Mesurement

Salivary and serum TNF-α levels were measured by ELISA

Sponsors & Collaborators

  • Istanbul Medipol University Hospital

    collaborator OTHER

  • Ankara University

    collaborator OTHER

  • Acibadem University

    collaborator OTHER

  • Lokman Hekim University

    collaborator OTHER_GOV

  • Ankara Medipol University

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2024-01-08
Primary Completion
2024-08-14
Completion
2024-09-23

Countries

  • Turkey (Türkiye)

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06906510 on ClinicalTrials.gov