Cognitive Performance and Mood After Ingestion of Dietary Supplement by University Students

Summary

This study investigates the effect of dietary supplementation on cognitive Performance and mood in university students over a 60-day period using a double-blind randomized controlled design. This study includes 75 participants, aged 18 or older. Participants will be randomly assigned to group I (n=25; will receive the supplement one), group II (n=25; will receive the supplement two), and group III (n=25; control/placebo).

Assessments will be conducted before starting supplementation, 30 days after, and at the end of the intervention to determine the effect of the supplementation on cognitive performance and mood. The main outcomes include cognitive status and mood measured by Depression Anxiety Stress Scales - (DASS), Brief Symptom Inventory (BSI) and Self-efficacy scale in higher education. Adherence to supplementation and potential side effects will also be assessed.

Based on the data obtained at these three assessment points, it will be possible to qualitatively address the actual effect of supplements on students' cognitive performance.

In addition, the participants nutritional status will also be assessed using the Simplified Appetite Nutrition Questionnaire (SANQ) and their perception of it using the Visual Appetite Scale (VAS). Both measurements will take place before the start of supplementation and at the end of the intervention.

Conditions

• Cognitive Performance
• Mood
• Dietary Supplement
• Safety

Interventions

OTHER

Placebo

Participants in this arm will receive a daily dose of an inert placebo that matches the supplement in appearance, taken orally for 60 consecutive days. The placebo is used as a control to compare the effects of the dietary supplement on cognitive performance. Participants will undergo the same cognitive assessments as the experimental groups.

DIETARY_SUPPLEMENT

Dietary Supplement

Dietary Supplements Participants in this arm will receive a daily dose of two dietary supplement for 60 consecutive days. The supplements are administered orally and aims to improve cognitive performance in university students. Participants will also complete cognitive assessments before starting supplementation, 30 days after, and at the end of the intervention

Sponsors & Collaborators

• Cooperativa de Ensino Superior, Politécnico e Universitário

  lead OTHER

Principal Investigators

• Rui Linhares, MSc · Escola Superior de Saúde do Vale do Ave

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2025-01-02

Primary Completion

2025-06-30

Completion

2025-10-31

Countries

• Portugal

Study Locations